BIO-G-F-M miniature parallel glass fermenter
The Willong BIO-G-F-M series miniature glass parallel bioreactor system, standard configuration is a 4-parallel tank system (expandable to hundreds of parallel networks according to customer needs), is compact and space-saving, featuring advanced bioprocess control, automated operation and information management solutions, suitable for microbiology research and early process development. Features such as parallel process control, precise control of all relevant parameters, user-defined schemes and numerous automated control procedures make process development faster and more efficient. The Willong Ai-BIO software solution supports DoE, process history databases and comprehensive data management. Customizable solutions are available to meet unique application needs, such as high-throughput automated strain construction, screening and process development, and biosynthetic process research.
Keyword：
BIO-G-F-M miniature parallel glass fermenter
Category：
Product details
The Willong BIO-G-F-M series miniature glass parallel bioreactor system comes standard with a 4-parallel tank system (expandable to hundreds of parallel networks based on customer needs). It features a compact design with a small footprint, advanced bioprocess control, automated operation, and information management solutions, suitable for microbiology research and early process development. Parallel process control, precise control of all relevant parameters, user-defined schemes, and numerous automated control programs make process development faster and more efficient. The Willong Ai-BIO software solution supports DoE, process history databases, and comprehensive data management. Customizable solutions meet unique application needs, such as high-throughput automated strain construction, screening, process development, and biosynthetic process research.
Product Features
● Multiple bioreactors can be set in parallel (24/48/96 or more);
● Excellent scalability, parallelism, and reproducibility in microbial fermentation and cell culture applications;
● Small working volume, saving on cell, medium, and feed requirements;
● Semiconductor refrigeration system for cooling, eliminating the need for chilled water preparation, with individual tank temperature control;
● Water-free operation exhaust condenser is easy to operate; insert to activate, remove to close;
● LCD color display shows key process parameters, with built-in alarm function, simplifying monitoring requirements;
● Air, N₂, O₂, and CO₂ are independently controlled and mixed by four mass flow meters (optional), allowing for surface and deep aeration;
● Precise miniature variable-speed peristaltic pump with minimum flow control up to 0.3L/hour. Modular design of the control system allows for flexible system configuration to meet specific application needs;
● Magnetic coupling stirring system, zero leakage, no pollution, long life;
● Temperature, stirring, pH, level, and DO control (customizable cascade mode) in each bioreactor;
● Variable speed pumps accurately add liquids in batch, fed-batch, continuous, and perfusion modes;
● Online calculation of absorbance values, such as OD600 or cell dry weight; online calculation of OTR, CTR, and RQ values;
● Compatible with Willong Ai-BIO for interconnection and bioprocess information management.
● High parallelism, synchronization of signal acquisition and command sending, ensuring operational parallelism, data comparability, and result validity. One-button start/stop of the same group of fermenters, one-button calibration of temperature, pH, DO, etc., sensors of multiple bioreactors, and one-button synchronization of setting parameters to all reactors can be achieved.
● Miniaturization aimed at scale-up, ultimately aiming to facilitate subsequent process scale-up. During reactor miniaturization, full consideration is given to maintaining as much consistency as possible with production tanks in terms of structure, flow field characteristics, and control methods.
| Tank | Total Volume | 387ML | 500ML | 1250ML | 2200ML |
| Material | Glass tank: Sterilizable high-temperature borosilicate glass; Tank lid: 316L stainless steel | ||||
| Control | Standard | Mainboard chip control: One-button setting, one-button calibration, synchronous signal acquisition, synchronous command sending | |||
| Options | Optional Willong AI-BIO for powerful data acquisition, analysis, and internet monitoring functions/mobile APP | ||||
| Sterilization | Sterilization Method | In-situ empty tank sterilization, in-situ full tank sterilization (the motor must be removed before sterilization) | |||
| Sterilization Temperature | Sterilization temperature: 100-135℃, Sterilization time: 0-60min | ||||
| Temperature Control | Control Method | Semiconductor heating and cooling | |||
| Range | 15℃-60℃±0.2℃ | ||||
| pH | Control Method | Peristaltic pump associated control for alkali addition, acid pump and CO₂ gas flow associated control for acid supplementation | |||
| Range | Display range: 0-14pH, Control range: 2-12±0.1pH | ||||
| DO | Control Method | Dissolved oxygen controlled by stirring and Air, O₂, N₂ gas flow mixing | |||
| Range | Display range: 0-200%, Control range: 0-100%±1% | ||||
| Stirring | Control Method | Top-mounted zero-leakage magnetic drive, stepless speed control with servo motor | |||
| Range Impeller |
0-350±1rpm (cell culture), 0-1500±1rpm (microbial fermentation) Elephant Ear impeller (cell culture) or Rushton impeller (microbial fermentation) |
||||
| Aeration | Control Method | Automatic analog control (gas flow rate for each channel is automatically determined by mass flow meter) Automatic solenoid valve proportional control (gas opening flow rate for each channel is manually set by rotor flow meter) |
|||
| Gas Distributor | Micro-bubble or large bubble optional Annular porous distributor or L-type distributor optional |
||||
| Feeding | Control Method | Peristaltic pump control, standard 4-channel feeding per tank, speed of each pump can be set individually, continuously adjustable | |||
| Other Notes | Each pump's function can be set individually: each can be used as an acid pump, alkali pump, feed pump, or defoaming pump | ||||
| Exhaust | Standard | Semiconductor refrigeration exhaust condenser | |||
| Other Notes | Sterilized with the tank during sterilization | ||||
| Defoaming | Measurement | Height-adjustable resistive foam sensor | |||
| Control Method | Associated with the defoaming peristaltic pump to achieve automatic defoaming | ||||
Previous page
Previous
BIO-G-F-D small desktop glass fermenter
Product consultation
Enter your contact information, and our sales team will contact you immediately to understand your needs.
Contact Us
Address: No. 48, Gaoxin Avenue, High-tech Development Zone, Fuzhou, Fujian Province, China Southeast (Fujian) Science City C3# Building, 5th Floor, New Productivity Cultivation Center
Postcode: 350108
Tel: +86-591-83210809
Hotline: 400-886-2316
Email: weilang@bio-wl.com